P2.04-019 A Peripheral Immune Signature Associated with Clinical Activity of Sunitinib in Thymic Carcinoma
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Sunitinib Induced Immune Thrombocytopenia
Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...
متن کاملSunitinib Induced Immune Thrombocytopenia
Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...
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Hepatitis A infection is usually a self–limited disease during childhood. Autoimmune manifestations are rarely reported among patients with HA infection. We describe a previously healthy 6-yr-old male with acute hepatitis A who developed immune thrombocytopenia.
متن کاملEvaluation of Immunohistochemical Findings and Clinical Features associated with Local Aggressiveness in Basal Cell Carcinoma
Background & Objective:Basal cell carcinoma (BCC) is classified into BCC1 or low risk (nodular, superficial type) and BCC2 or high risk (micronodular, morpheaform, infiltrative, and basosquamous types) based on clinical behavior. This study attempts to evaluate immunohistochemical (IHC) findings and clinical features associated with local aggressiveness and recurrence ...
متن کاملScleromyxedema: a cutaneous paraneoplastic syndrome associated with thymic carcinoma.
Introduction Although it is a rare disorder, scleromyxedema (lichen myxedematosus) is one of the most common forms of primary cutaneous mucinosis. This condition is a generalized form of dermal mucin deposition characterized by waxy papules that progresses to indurated and thickened skin and is often associated with monoclonal gammopathy, particularly of the immunoglobulin G type. Lichen myxede...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2017
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2016.11.1399